Salmonella control in broilers to improve food safety


Salmonella is responsible for approximately 1 million foodborne illnesses a year in the US and 91,000 in Europe. Salmonella contamination is a global issue in poultry production. Interventions are applied in processing plants to reduce the contamination of poultry products, although the real solution is to prevent the arrival of contaminated broilers, turkeys or eggs in processing plants in the first place. Prevention at farm level is very important in reducing the risk of poultry meat or table egg contamination..

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Salmonella contamination in poultry farms

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Salmonella can come from feed: through additives and thermisation


Salmonella can linger in poultry houses, which remain contaminated from a previous batch of birds and are poorly disinfected, or contaminated because of rodents, insects etc.


Salmonella can arrive with contaminated day-old chicks, after vertical transmission in the egg or by the contamination of the egg shell when passing through the cloaca.

Salmonella control
Salmonella control

Reducing Salmonella pressure in the gut

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As Safmannan® contains high concentrations of mannans and beta-glucans, diet supplementation with the product enables the adherence of Salmonella to mannans of Safmannan®, thus reducing gut Salmonella pressures during faeces excretion.


Beta-glucans and mannans modulate the immune function, with higher antibody levels released at the surface of the gut epithelium: more secretory IgA targeting Salmonella.


Safmannan® helps preserve tight junctions for less Salmonella translocation from gut content to deep organs, such as the liver, spleen, or even the ovary grape (relevant for layers and breeders).

Trials with Safmannan®

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A 2018 trial by C. Hofacre in SPRG, based on a 40-pen study, involved placing 2000 chicks into 5 treatment groups. The trial featured Safmannan® at different doses and a commercial yeast culture product. 25 day-old chicks per pen were tagged, colour-coded, and orally gavaged with 5×107 CFU of Salmonella Heidelberg. 25 more chicks (contact birds) per pen were not challenged, thus being potentially contaminated by the challenged chicks.


Safmannan® at 500 g/T significantly reduced the number of S. Heidelberg in the ceca of contact birds at D42, using the Most Probable Number (MPN) method.

Salmonella control
Salmonella control

Safmannan® helps the immune system be more efficient against Salmonella

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A 2019 trial by Imunova, Brazil, involved 35 day-old birds, assigned to 3 treatment groups: non-challenged/non-supplemented; challenged/non-supplemented; and challenged/supplemented with Safmannan® at 250 g/T from D1 to D28. The challenge of 108 CFU of Salmonella Typhimurium was given orally on D2 .


Safmannan® helped the immune system produce significantly more secretory IgA against LPS and Flagellin of Salmonella at day 28. Moreover, the histopathology score was significantly reduced at day 28.

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Strategies to reduce Salmonella prevalence in the poultry industry


Find out more about broiler management

gut health broilers
antibiotics reduction broilers
heat stress
Immune modulation
oxydation stress

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