Microsaf® the new generation probiotic powered by patented
GO Technology®


In modern poultry farming, it is essential to support birds’ gut function, decrease pathogen pressure and improve feed efficiency. Some selected spore-forming bacteria probiotics boost resistance to the demands of today’s production processes, while also delivering proven gut health benefits after germination. However, with the average transition time in the poultry gut being only 4 to 6 hours. The key question is how to achieve maximum impact from spore-forming bacteria probiotics in the poultry gut during such a short transition time.

Microsaf®, the new generation probiotic, powered by patented GO Technology®, is a unique association of Bacillus species, Bacillus amyloliquefaciens, Bacillus licheniformis, Bacillus pumilus, carefully selected to deliver improvements in feed efficiency, gut function, and microbiota, and overall growth performance in birds.

The performance of Microsaf® is enhanced by the exclusive 3-patent Germination Optimisation Technology, a new process designed to promote faster and stronger Bacillus spore germination. This maximises the impact of Microsaf® within the short transit time of 4-6 hours, which applies to most chickens.

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of our customers

Microsaf® improves growth by increasing feed efficiency

GO Technology® allows Microsaf® to germinate under challenging conditions due to the short transit time in chickens, mitigating the negative impacts of acidic pH and bile salts.


Bacillus amyloliquefaciens has been screened for its high capacity in the production of enzymes such as Protease, Amylase and Lipase. Adding Microsaf® to a bird’s diet can achieve improved feed intake, feed efficiency and growth.

Microsaf® preserves gut function by decreasing the risk of bacterial enteritis

Microsaf® has shown high capacity lactic acid production and consistent effects in the inhibition of major poultry pathogens such as Clostridium perfringens, Escherichia coli (E. coli) and Campylobacter jejuni.


Under a Clostridium perfringens challenge, supplementing the diet with Microsaf® helps the birds to achieve higher levels of feed intake, improved FCR, higher daily growth rates and a better all-round growth performance.

Microsaf® enhances food safety by decreasing Salmonella prevalence

Salmonella is a significant cause of foodborne illness worldwide.A recent peer-reviewed article demonstrated that Microsaf® is a possible pre-harvest food safety intervention, reducing Salmonella load in the ceca, thus reducing possible contamination to the environment and consequently the eggshell.

Microsaf® multi-species bacteria probiotic powered by GO Technology® for faster and stronger benefits

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Microsaf® is the association of 3 Bacillus species selected through a battery of screening tests from a library of proprietary strains.


Microsaf® is a spore-forming bacteria probiotic with a high resistance to feed processes, such as high temperatures during pelleting or the heat treatment of mash feed.


Microsaf® is available in two different concentrations:

  • Microsaf® 500, suitable for directly supplementing complete feeds
  • Microsaf® 20, suitable for incorporation into a premix

GO Technology® faster and stronger spore germination

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By priming the germination process with combined germinant factors for faster activation, GO Technology® can accelerate and synchronise Bacillus spore germination, mitigating the impact of challenging conditions such as acidic pH and the presence of bile salts.



Bacillus spores  has shown that GO Technology® innovation successfully accelerated and synchronised the germination of the 3 Microsaf® strains. This enabled primed Bacillus licheniformis spores to reach 90% germination in just 45 minutes, a level reached by only 10% of the spores in the control group.

Mode of action of Microsaf® new generation probiotic powered by patented GO Technology®

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The 3 Bacillus strains are chosen for their complementary mode of action. Microsaf® combines Bacillus amyloliquefaciens, which is the best performing strain for producing enzymes; Bacillus licheniformis, which is the best performing strain for producing lactic acid, and Bacillus pumilus, which is the best performing strain for phagocytosis activation. All 3 strains have a strong ability to inhibit major poultry pathogens, such as Clostridium perfringens, Escherichia coli (E. coli), Salmonella, Campylobacter jejuni and Staphylococcus aureus.

The information provided in this document is to the best of our knowledge, true and accurate. Not all products are available in all regions nor are the associated intended uses and/or claims the same in all regions. Products must only be used in compliance with local laws and regulations and we cannot guarantee freedom for every intended use or country.

microsaf pack

Responding to the needs of our customers



  • Microsaf® 20 : 5kg polyethylene bag, packed in corrugated cardboard box
  • Microsaf® : 500 20kg polyethylene bag, packed in corrugated cardboard box




  • Microsaf®offers a high stability with its long shelf life of 18 months




  • Please reach out to our Phileo experts here

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