{"id":408390,"date":"2021-09-07T10:16:15","date_gmt":"2021-09-07T08:16:15","guid":{"rendered":"https:\/\/phileo-lesaffre.com\/poulets-de-chair\/modulation-immunitaire-et-titres-danticorps-chez-le-poulet-de-chair\/"},"modified":"2021-09-13T11:14:45","modified_gmt":"2021-09-13T09:14:45","slug":"modulation-immunitaire-et-titres-danticorps-chez-le-poulet-de-chair","status":"publish","type":"page","link":"https:\/\/phileo-lesaffre.com\/fr\/poulets-de-chair\/modulation-immunitaire-et-titres-danticorps-chez-le-poulet-de-chair\/","title":{"rendered":"Modulation immunitaire et titres d\u2019anticorps chez le poulet de chair"},"content":{"rendered":"

[vc_row css_animation=\u00a0\u00bb\u00a0\u00bb row_type=\u00a0\u00bbrow\u00a0\u00bb use_row_as_full_screen_section=\u00a0\u00bbno\u00a0\u00bb type=\u00a0\u00bbfull_width\u00a0\u00bb angled_section=\u00a0\u00bbno\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb background_image_as_pattern=\u00a0\u00bbwithout_pattern\u00a0\u00bb el_class=\u00a0\u00bbbreadcrumbtxt\u00a0\u00bb z_index=\u00a0\u00bb\u00a0\u00bb][vc_column][vc_column_text]Phileo by Lesaffre<\/a><\/span><\/span><\/span>[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=\u00a0\u00bb\u00a0\u00bb row_type=\u00a0\u00bbrow\u00a0\u00bb use_row_as_full_screen_section=\u00a0\u00bbno\u00a0\u00bb type=\u00a0\u00bbfull_width\u00a0\u00bb angled_section=\u00a0\u00bbno\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb background_image_as_pattern=\u00a0\u00bbwithout_pattern\u00a0\u00bb][vc_column][vc_column_text]<\/p>\n

[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=\u00a0\u00bb\u00a0\u00bb row_type=\u00a0\u00bbrow\u00a0\u00bb use_row_as_full_screen_section=\u00a0\u00bbno\u00a0\u00bb type=\u00a0\u00bbfull_width\u00a0\u00bb angled_section=\u00a0\u00bbno\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb background_image_as_pattern=\u00a0\u00bbwithout_pattern\u00a0\u00bb][vc_column][qode_elements_holder number_of_columns=\u00a0\u00bbtwo_columns\u00a0\u00bb][qode_elements_holder_item vertical_alignment=\u00a0\u00bbmiddle\u00a0\u00bb horizontal_alignment=\u00a0\u00bbleft\u00a0\u00bb advanced_animations=\u00a0\u00bbno\u00a0\u00bb item_padding=\u00a0\u00bb5% 8% 5% 0%\u00a0\u00bb][vc_column_text]<\/p>\n

Modulation immunitaire et titres d\u2019anticorps<\/span><\/h1>\n

[\/vc_column_text][vc_single_image image=\u00a0\u00bb407413″ img_size=\u00a0\u00bb65×33″ qode_css_animation=\u00a0\u00bb\u00a0\u00bb css=\u00a0\u00bb.vc_custom_1590613047306{padding-top: 5% !important;padding-bottom: 5% !important;}\u00a0\u00bb][vc_column_text css=\u00a0\u00bb.vc_custom_1610544940448{padding-right: 8% !important;}\u00a0\u00bb]La pr\u00e9vention des maladies exige une approche globale pour comprendre la contamination par les pathog\u00e8nes et l\u2019application de proc\u00e9dures de nettoyage et de d\u00e9sinfection sur l\u2019exploitation. La bios\u00e9curit\u00e9 est vitale.<\/p>\n

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Tous les facteurs de stress qui rendent les oiseaux plus sensibles \u00e0 la maladie doivent \u00eatre contr\u00f4l\u00e9s par une bonne gestion de l\u2019exploitation. Phileo by Lesaffre a d\u00e9velopp\u00e9 des solutions qui compl\u00e8tent les mesures de contr\u00f4le existantes, pour des oiseaux plus r\u00e9sistants aux maladies.<\/p>\n

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Safmannan<\/a>\u00ae<\/sup>, une fraction pari\u00e9tale de levure premium, riche en mannanes et en b\u00eata-glucanes 1,3 et 1,6, aide \u00e0 maintenir une bonne int\u00e9grit\u00e9 intestinale, \u00e0 pr\u00e9venir la contamination par des bact\u00e9ries pathog\u00e8nes (telles que E.coli<\/em>, Salmonella<\/em> et Clostridium<\/em>). Il aide \u00e9galement \u00e0 am\u00e9liorer le fonctionnement du syst\u00e8me immunitaire et la r\u00e9ponse vaccinale des oiseaux.[\/vc_column_text][vc_single_image image=\u00a0\u00bb407741″ img_size=\u00a0\u00bb120×178″ alignment=\u00a0\u00bbright\u00a0\u00bb qode_css_animation=\u00a0\u00bb\u00a0\u00bb][\/qode_elements_holder_item][qode_elements_holder_item cover=\u00a0\u00bbyes\u00a0\u00bb vertical_alignment=\u00a0\u00bbmiddle\u00a0\u00bb horizontal_alignment=\u00a0\u00bbleft\u00a0\u00bb advanced_animations=\u00a0\u00bbno\u00a0\u00bb background_image=\u00a0\u00bb397730″][\/qode_elements_holder_item][\/qode_elements_holder][\/vc_column][\/vc_row][vc_row css_animation=\u00a0\u00bb\u00a0\u00bb row_type=\u00a0\u00bbrow\u00a0\u00bb use_row_as_full_screen_section=\u00a0\u00bbno\u00a0\u00bb type=\u00a0\u00bbfull_width\u00a0\u00bb angled_section=\u00a0\u00bbno\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb background_image_as_pattern=\u00a0\u00bbwithout_pattern\u00a0\u00bb z_index=\u00a0\u00bb\u00a0\u00bb][vc_column][qode_elements_holder number_of_columns=\u00a0\u00bbtwo_columns\u00a0\u00bb][qode_elements_holder_item cover=\u00a0\u00bbyes\u00a0\u00bb advanced_animations=\u00a0\u00bbno\u00a0\u00bb background_image=\u00a0\u00bb397706″][\/qode_elements_holder_item][qode_elements_holder_item vertical_alignment=\u00a0\u00bbmiddle\u00a0\u00bb horizontal_alignment=\u00a0\u00bbleft\u00a0\u00bb advanced_animations=\u00a0\u00bbno\u00a0\u00bb item_padding=\u00a0\u00bb5% 2% 5% 10%\u00a0\u00bb background_color=\u00a0\u00bb#e58734″][vc_column_text]<\/p>\n

Augmentation des barri\u00e8res du syst\u00e8me immunitaire inn\u00e9<\/span><\/h2>\n

[\/vc_column_text][vc_single_image image=\u00a0\u00bb409029″ img_size=\u00a0\u00bb50×25″ qode_css_animation=\u00a0\u00bb\u00a0\u00bb css=\u00a0\u00bb.vc_custom_1592227932921{padding-top: 5% !important;padding-bottom: 5% !important;}\u00a0\u00bb][vc_column_text css=\u00a0\u00bb.vc_custom_1593163068293{padding-right: 10% !important;}\u00a0\u00bb]Il est possible d\u2019aider le syst\u00e8me immunitaire adaptatif \u00e0 \u00eatre plus efficace apr\u00e8s une vaccination. Cette raison sp\u00e9cifique est associ\u00e9e \u00e0 une immunit\u00e9 non sp\u00e9cifique, ou inn\u00e9e.<\/span><\/p>\n

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La premi\u00e8re ligne de d\u00e9fense se compose de barri\u00e8res physiques (peau, \u00e9pith\u00e9lium, jonctions serr\u00e9es, mucus sur les cellules \u00e9pith\u00e9liales, battement des cils de la trach\u00e9e, p\u00e9ristaltisme intestinal), barri\u00e8res chimiques (acides gras, lysozyme, acidit\u00e9 du pH du proventricule, peptides antibact\u00e9riens) et barri\u00e8res microbiologiques.<\/span><\/p>\n

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La deuxi\u00e8me ligne de d\u00e9fense se compose de phagocytes, capables d\u2019\u00e9liminer les bact\u00e9ries opsonis\u00e9es par le syst\u00e8me compl\u00e9mentaire et les mastocytes, capables de r\u00e9veiller le syst\u00e8me immunitaire en cas d\u2019infection. Enfin, il se compose de cellules tueuses naturelles, capables de tuer directement les cellules infect\u00e9es par des virus ou les cellules tumorales.<\/span>[\/vc_column_text][\/qode_elements_holder_item][\/qode_elements_holder][\/vc_column][\/vc_row][vc_row css_animation=\u00a0\u00bb\u00a0\u00bb row_type=\u00a0\u00bbrow\u00a0\u00bb use_row_as_full_screen_section=\u00a0\u00bbno\u00a0\u00bb type=\u00a0\u00bbfull_width\u00a0\u00bb angled_section=\u00a0\u00bbno\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb background_image_as_pattern=\u00a0\u00bbwithout_pattern\u00a0\u00bb css=\u00a0\u00bb.vc_custom_1592234497567{background-color: #ffffff !important;}\u00a0\u00bb z_index=\u00a0\u00bb\u00a0\u00bb][vc_column][qode_elements_holder number_of_columns=\u00a0\u00bbtwo_columns\u00a0\u00bb][qode_elements_holder_item vertical_alignment=\u00a0\u00bbmiddle\u00a0\u00bb horizontal_alignment=\u00a0\u00bbleft\u00a0\u00bb advanced_animations=\u00a0\u00bbno\u00a0\u00bb item_padding=\u00a0\u00bb5% 10% 5% 5%\u00a0\u00bb background_color=\u00a0\u00bb#706f6f\u00a0\u00bb][vc_column_text]<\/p>\n

Pr\u00e9servation de la bonne int\u00e9grit\u00e9 intestinale<\/span><\/h2>\n

[\/vc_column_text][vc_single_image image=\u00a0\u00bb409029″ img_size=\u00a0\u00bb50×25″ qode_css_animation=\u00a0\u00bb\u00a0\u00bb css=\u00a0\u00bb.vc_custom_1592232787710{padding-top: 5% !important;padding-bottom: 5% !important;}\u00a0\u00bb][vc_column_text]Comme 70 % de la capacit\u00e9 du syst\u00e8me immunitaire des oiseaux se situe dans le tube digestif, il est important de pr\u00e9server une bonne int\u00e9grit\u00e9 intestinale. L\u2019inflammation intestinale chronique, due \u00e0 une importante ingestion alimentaire par les races modernes de volaille, doit \u00eatre contr\u00f4l\u00e9e. Safmannan peut aider le syst\u00e8me immunitaire inn\u00e9 \u00e0 \u00eatre mieux pr\u00e9par\u00e9 contre une infection. Ceci est possible par le mode d\u2019action suivant :<\/span><\/p>\n

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\u2022 Liaison aux pathog\u00e8nes
\n\u2022 Augmentation de la num\u00e9ration des cellules caliciformes
\n\u2022 Modulation de l\u2019inflammation
\n<\/span>[\/vc_column_text][\/qode_elements_holder_item][qode_elements_holder_item cover=\u00a0\u00bbyes\u00a0\u00bb advanced_animations=\u00a0\u00bbno\u00a0\u00bb background_image=\u00a0\u00bb396525″][vc_separator type=\u00a0\u00bbtransparent\u00a0\u00bb up=\u00a0\u00bb200″ down=\u00a0\u00bb200″][\/qode_elements_holder_item][\/qode_elements_holder][\/vc_column][\/vc_row][vc_row css_animation=\u00a0\u00bb\u00a0\u00bb row_type=\u00a0\u00bbrow\u00a0\u00bb use_row_as_full_screen_section=\u00a0\u00bbno\u00a0\u00bb type=\u00a0\u00bbfull_width\u00a0\u00bb angled_section=\u00a0\u00bbno\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb background_image_as_pattern=\u00a0\u00bbwithout_pattern\u00a0\u00bb z_index=\u00a0\u00bb\u00a0\u00bb][vc_column][qode_elements_holder number_of_columns=\u00a0\u00bbtwo_columns\u00a0\u00bb][qode_elements_holder_item advanced_animations=\u00a0\u00bbno\u00a0\u00bb][vc_single_image image=\u00a0\u00bb409358″ img_size=\u00a0\u00bbfull\u00a0\u00bb onclick=\u00a0\u00bblink_image\u00a0\u00bb qode_css_animation=\u00a0\u00bb\u00a0\u00bb qode_hover_animation=\u00a0\u00bbzoom_in\u00a0\u00bb][\/qode_elements_holder_item][qode_elements_holder_item vertical_alignment=\u00a0\u00bbmiddle\u00a0\u00bb horizontal_alignment=\u00a0\u00bbleft\u00a0\u00bb advanced_animations=\u00a0\u00bbno\u00a0\u00bb item_padding=\u00a0\u00bb5% 2% 5% 10%\u00a0\u00bb background_color=\u00a0\u00bb#e58734″][vc_column_text]<\/p>\n

Effets de Safmannan\u00ae<\/sup> sur la modulation du syst\u00e8me immunitaire<\/span><\/h2>\n

[\/vc_column_text][vc_single_image image=\u00a0\u00bb409029″ img_size=\u00a0\u00bb50×25″ qode_css_animation=\u00a0\u00bb\u00a0\u00bb css=\u00a0\u00bb.vc_custom_1592232787710{padding-top: 5% !important;padding-bottom: 5% !important;}\u00a0\u00bb][vc_column_text]Plusieurs \u00e9tudes men\u00e9es dans des exploitations de recherche et d\u00e9veloppement montrent ces effets, \u00e0 la suite de diff\u00e9rentes vaccinations, contre la maladie de Newcastle (ND) ou l\u2019influenza aviaire (H5 ou H9) par exemple. Dans cette \u00e9tude, les poulets de chair ont \u00e9t\u00e9 vaccin\u00e9s \u00e0 10 jours d’\u00e2ge avec un vaccin vivant contre la ND et nourris avec une alimentation suppl\u00e9ment\u00e9e avec Safmannan<\/a>\u00ae<\/sup> ou une alimentation de contr\u00f4le. Des \u00e9chantillons sanguins ont \u00e9t\u00e9 pr\u00e9lev\u00e9s les semaines 1 et 2 apr\u00e8s la vaccination et analys\u00e9es par un test HI. Deux semaines apr\u00e8s la vaccination, la r\u00e9ponse vaccinale du groupe suppl\u00e9ment\u00e9 avec Safmannan<\/a>\u00ae<\/sup> \u00e9tait significativement sup\u00e9rieure \u00e0 celle du groupe de contr\u00f4le.<\/span>[\/vc_column_text][\/qode_elements_holder_item][\/qode_elements_holder][\/vc_column][\/vc_row][vc_row css_animation=\u00a0\u00bb\u00a0\u00bb row_type=\u00a0\u00bbrow\u00a0\u00bb use_row_as_full_screen_section=\u00a0\u00bbno\u00a0\u00bb type=\u00a0\u00bbfull_width\u00a0\u00bb angled_section=\u00a0\u00bbno\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb background_image_as_pattern=\u00a0\u00bbwithout_pattern\u00a0\u00bb z_index=\u00a0\u00bb\u00a0\u00bb][vc_column][qode_elements_holder number_of_columns=\u00a0\u00bbtwo_columns\u00a0\u00bb][qode_elements_holder_item vertical_alignment=\u00a0\u00bbmiddle\u00a0\u00bb horizontal_alignment=\u00a0\u00bbleft\u00a0\u00bb advanced_animations=\u00a0\u00bbno\u00a0\u00bb item_padding=\u00a0\u00bb5% 2% 5% 10%\u00a0\u00bb background_color=\u00a0\u00bb#706f6f\u00a0\u00bb][vc_column_text]<\/p>\n

Effets de Safglucan\u00ae<\/sup> sur l\u2019immunit\u00e9 entra\u00een\u00e9e<\/span><\/h2>\n

[\/vc_column_text][vc_single_image image=\u00a0\u00bb409029″ img_size=\u00a0\u00bb50×25″ qode_css_animation=\u00a0\u00bb\u00a0\u00bb css=\u00a0\u00bb.vc_custom_1592232787710{padding-top: 5% !important;padding-bottom: 5% !important;}\u00a0\u00bb][vc_column_text]Phileo by Lesaffre a \u00e9galement d\u00e9velopp\u00e9 une solution appel\u00e9e Safglucan<\/a>\u00ae, dans laquelle des b\u00eata-glucanes 1,3 et 1,6 sont purifi\u00e9s et s\u00e9par\u00e9s des fractions de mannanes, pour atteindre plus de 50 % de la composition du produit. Son activit\u00e9 cible davantage le syst\u00e8me immunitaire quand Safmannan<\/a>\u00ae<\/sup> a un effet plus large.
\nPlusieurs essais in vivo<\/em> ont montr\u00e9 l\u2019effet b\u00e9n\u00e9fique de Safglucan<\/a>\u00ae<\/sup> pour am\u00e9liorer la r\u00e9ponse vaccinale.<\/span><\/p>\n

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\nDans cette \u00e9tude, Safglucan<\/a>\u00ae<\/sup> a \u00e9t\u00e9 utilis\u00e9 \u00e0 raison de 125 g\/tonne pour montrer son effet apr\u00e8s une vaccination contre la ND avec un vaccin inactiv\u00e9, inject\u00e9 aux jours 12 et 24. La r\u00e9ponse vaccinale est plus rapide et r\u00e9sistante par rapport au groupe de contr\u00f4le vaccin\u00e9.<\/span>[\/vc_column_text][\/qode_elements_holder_item][qode_elements_holder_item advanced_animations=\u00a0\u00bbno\u00a0\u00bb][vc_single_image image=\u00a0\u00bb409362″ img_size=\u00a0\u00bbfull\u00a0\u00bb onclick=\u00a0\u00bblink_image\u00a0\u00bb qode_css_animation=\u00a0\u00bb\u00a0\u00bb qode_hover_animation=\u00a0\u00bbzoom_in\u00a0\u00bb][\/qode_elements_holder_item][\/qode_elements_holder][vc_separator type=\u00a0\u00bbtransparent\u00a0\u00bb][\/vc_column][\/vc_row][vc_row css_animation=\u00a0\u00bb\u00a0\u00bb row_type=\u00a0\u00bbrow\u00a0\u00bb use_row_as_full_screen_section=\u00a0\u00bbyes\u00a0\u00bb type=\u00a0\u00bbfull_width\u00a0\u00bb angled_section=\u00a0\u00bbno\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb background_image_as_pattern=\u00a0\u00bbwithout_pattern\u00a0\u00bb z_index=\u00a0\u00bb\u00a0\u00bb][vc_column][vc_separator type=\u00a0\u00bbtransparent\u00a0\u00bb up=\u00a0\u00bb10″ down=\u00a0\u00bb10″][vc_column_text css=\u00a0\u00bb.vc_custom_1593402547571{padding-top: 2% !important;padding-bottom: 2% !important;}\u00a0\u00bb]<\/p>\n

Informez-vous sur la prise en charge du poulet de chair<\/span><\/h2>\n

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