{"id":898,"date":"2020-06-12T10:19:11","date_gmt":"2020-06-12T08:19:11","guid":{"rendered":"https:\/\/demo14.lesaffre.misyl.net\/?page_id=898"},"modified":"2025-05-15T09:47:20","modified_gmt":"2025-05-15T07:47:20","slug":"safmannan","status":"publish","type":"page","link":"https:\/\/phileo-lesaffre.com\/en\/safmannan\/","title":{"rendered":"Safmannan"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; el_class=&#8221;breadcrumbtxt&#8221; z_index=&#8221;&#8221;][vc_column][vc_column_text]<span style=\"font-size: 12px;\"><span><span><a href=\"https:\/\/phileo-lesaffre.com\/en\/\">Phileo by Lesaffre<\/a><\/span><\/span><\/span>[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][qode_elements_holder number_of_columns=&#8221;two_columns&#8221;][qode_elements_holder_item vertical_alignment=&#8221;middle&#8221; horizontal_alignment=&#8221;left&#8221; advanced_animations=&#8221;no&#8221; item_padding=&#8221;5% 10% 5% 0%&#8221;][vc_column_text]<\/p>\n<h1 class=\"feed2\"><span style=\"color: #4d4d4c;\">Safmannan<sup>\u00ae<\/sup> the reference yeast postbiotic for animals\u2019 better performance and resilience<\/span><\/h1>\n<p>[\/vc_column_text][vc_single_image image=&#8221;385&#8243; img_size=&#8221;65&#215;33&#8243; css=&#8221;.vc_custom_1590613257454{padding-top: 5% !important;padding-bottom: 5% !important;}&#8221; qode_css_animation=&#8221;&#8221;][vc_column_text css=&#8221;.vc_custom_1622715949270{padding-right: 10% !important;}&#8221;]Farm animals face multiple stress, including pathogen pressures, high stocking densities, intensive growth, longer production periods, and heat stress. Key questions include how to protect animals against stress and how to improve animals\u2019 production performance under challenging conditions.<br \/>\nThe positive effects of Safmannan<sup>\u00ae<\/sup> have been demonstrated in many species including poultry, farmed fish and pets. The product\u2019s impact has been proven globally through a battery of in vitro and in vivo tests, in cooperation with independent world-class research centres.<\/p>\n<p>&nbsp;<\/p>\n<p>Adding Safmannan<sup>\u00ae<\/sup> to animal diets may help support gastrointestinal balance, preserve gut integrity, and modulate immunity. Safmannan<sup>\u00ae<\/sup> may help to mitigate the detrimental effects of stress and improve feed efficiency, animal performance, and food safety.[\/vc_column_text][\/qode_elements_holder_item][qode_elements_holder_item cover=&#8221;yes&#8221; vertical_alignment=&#8221;middle&#8221; horizontal_alignment=&#8221;left&#8221; advanced_animations=&#8221;no&#8221; background_image=&#8221;397744&#8243;][\/qode_elements_holder_item][\/qode_elements_holder][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; css=&#8221;.vc_custom_1589696078251{padding-top: 1% !important;padding-bottom: 1% !important;}&#8221; z_index=&#8221;&#8221;][vc_column][vc_video link=&#8221;https:\/\/vimeo.com\/901507395&#8243; align=&#8221;center&#8221;][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;yes&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; z_index=&#8221;&#8221; css=&#8221;.vc_custom_1590613315117{padding-top: 1% !important;padding-bottom: 2% !important;}&#8221;][vc_column][vc_column_text]<\/p>\n<h2 class=\"feed2\"><span style=\"color: #4d4d4c;\">Responding to the needs<br \/>\nof our customers<\/span><\/h2>\n<p>[\/vc_column_text][vc_separator type=&#8221;transparent&#8221; up=&#8221;15&#8243; down=&#8221;15&#8243;][\/vc_column][vc_column width=&#8221;1\/3&#8243; css=&#8221;.vc_custom_1589951433309{padding-top: 15px !important;padding-right: 25px !important;padding-bottom: 15px !important;padding-left: 25px !important;}&#8221;][vc_column_text css=&#8221;.vc_custom_1622716555531{padding-top: 10% !important;padding-right: 10% !important;padding-bottom: 10% !important;padding-left: 10% !important;background-color: #706f6f !important;}&#8221; el_class=&#8221;bloc&#8221;]<\/p>\n<h3><span style=\"color: #ffffff;\">Safmannan<sup>\u00ae<\/sup> improves gut function<\/span><\/h3>\n<p>[vc_separator type=&#8221;transparent&#8221; up=&#8221;5&#8243; down=&#8221;5&#8243;]<br \/>\n<span style=\"color: #ffffff;\">Increasing the number of beneficial bacteria in the intestinal tract to counteract the colonization by bacterial pathogens such as <em>Salmonella<\/em>, <em>E.\u00a0coli<\/em>, <em>Vibrio spp.<\/em>, and <em>Clostridia<\/em> is essential. Safmannan\u00ae may help to maintain intestinal integrity and defence barriers. Safmannan<sup>\u00ae<\/sup> balances microbiota, supports gut integrity, and promotes gut function, thus improving feed efficiency, production performance in animals and mitigating the negative effects of stress, such as heat stress.<\/span>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/3&#8243; css=&#8221;.vc_custom_1589951537170{padding-top: 15px !important;padding-right: 25px !important;padding-bottom: 15px !important;padding-left: 25px !important;}&#8221;][vc_column_text css=&#8221;.vc_custom_1622718638507{padding-top: 10% !important;padding-right: 10% !important;padding-bottom: 10% !important;padding-left: 10% !important;background-color: #e58734 !important;}&#8221; el_class=&#8221;bloc&#8221;]<\/p>\n<h3><span style=\"color: #ffffff;\">Safmannan<sup>\u00ae<\/sup> strengthens animals\u2019 resilience, to limit the use of antibiotics<\/span><\/h3>\n<p>[vc_separator type=&#8221;transparent&#8221; up=&#8221;5&#8243; down=&#8221;5&#8243;]<br \/>\n<span style=\"color: #ffffff;\">Pathogen control, gut function preservation, and the enhancement of natural defences contribute to the wellbeing of animals. Safmannan<sup>\u00ae<\/sup> may help to strengthen animals\u2019 resilience, mitigate negative effects of stress like heat stress in the context of antibiotic reduction.<\/span>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/3&#8243; css=&#8221;.vc_custom_1589951530829{padding-top: 15px !important;padding-right: 25px !important;padding-bottom: 15px !important;padding-left: 25px !important;}&#8221;][vc_column_text css=&#8221;.vc_custom_1622718706349{padding-top: 10% !important;padding-right: 10% !important;padding-bottom: 10% !important;padding-left: 10% !important;background-color: #e58734 !important;}&#8221; el_class=&#8221;bloc&#8221;]<\/p>\n<h3><span style=\"color: #ffffff;\">Safmannan<sup>\u00ae<\/sup> helps to mitigate <em>Salmonella <\/em>prevalence and enhance food safety<\/span><\/h3>\n<p>[vc_separator type=&#8221;transparent&#8221; up=&#8221;5&#8243; down=&#8221;5&#8243;]<br \/>\n<span style=\"color: #ffffff;\"> <em>Salmonella Enteritidis<\/em> and <em>Salmonella<\/em> <em>Typhimurium<\/em> are the most common <em>Salmonella <\/em> serovars associated with foodborne illnesses in humans. Given the positive effect of Safmannan<sup>\u00ae<\/sup> on natural defences, microbiota balance and gut function improvement, adding Safmannan<sup>\u00ae<\/sup> to animal diets may contribute to food safety, early in the food, meat, and egg production chain.<\/span>[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][qode_elements_holder number_of_columns=&#8221;two_columns&#8221;][qode_elements_holder_item vertical_alignment=&#8221;middle&#8221; horizontal_alignment=&#8221;left&#8221; advanced_animations=&#8221;no&#8221; item_padding=&#8221;5% 10% 5% 10%&#8221; background_color=&#8221;#e58734&#8243;][vc_column_text]<\/p>\n<h2 class=\"feed4\"><span style=\"color: #ffffff;\">Safmannan<sup>\u00ae<\/sup> consistent premium quality leads to predictable performance<\/span><\/h2>\n<p>[\/vc_column_text][vc_single_image image=&#8221;27&#8243; img_size=&#8221;50&#215;25&#8243; css=&#8221;.vc_custom_1591894886108{padding-top: 5% !important;padding-bottom: 5% !important;}&#8221; qode_css_animation=&#8221;&#8221;][vc_column_text css=&#8221;.vc_custom_1747295235815{padding-right: 10% !important;}&#8221;]<span style=\"color: #ffffff;\">Safmannan<sup>\u00ae<\/sup> is a premium yeast postbiotic, rich in mannan-oligosaccharides and beta-glucans (1.3 and 1.6). It is obtained from primary culture and the purification of selected <em>Saccharomyces cerevisiae<\/em>. Fully controlled manufacturing processes and quality certifications ensure that Safmannan<sup>\u00ae<\/sup> meets the highest standards of ingredients and batch-to-batch consistency, providing significantly better benefits than other commercial yeast cell wall products.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ffffff;\">The consistent concentration of mannans (\u2265 20%) and beta-glucans (\u2265 20%) in the composition of Safmannan<sup>\u00ae<\/sup>, results in predictable high-performance outcomes.<\/span>[\/vc_column_text][\/qode_elements_holder_item][qode_elements_holder_item cover=&#8221;yes&#8221; vertical_alignment=&#8221;middle&#8221; horizontal_alignment=&#8221;left&#8221; advanced_animations=&#8221;no&#8221; background_image=&#8221;396768&#8243;][vc_separator type=&#8221;transparent&#8221; up=&#8221;200&#8243; down=&#8221;200&#8243;][\/qode_elements_holder_item][\/qode_elements_holder][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; z_index=&#8221;&#8221; anchor=&#8221;sustainability&#8221;][vc_column][qode_elements_holder number_of_columns=&#8221;two_columns&#8221;][qode_elements_holder_item cover=&#8221;yes&#8221; vertical_alignment=&#8221;middle&#8221; horizontal_alignment=&#8221;left&#8221; advanced_animations=&#8221;no&#8221; background_image=&#8221;869&#8243;][vc_separator type=&#8221;transparent&#8221; up=&#8221;200&#8243; down=&#8221;200&#8243;][\/qode_elements_holder_item][qode_elements_holder_item vertical_alignment=&#8221;middle&#8221; horizontal_alignment=&#8221;left&#8221; advanced_animations=&#8221;no&#8221; item_padding=&#8221;5% 10% 5% 10%&#8221; background_color=&#8221;#706f6f&#8221;][vc_column_text]<\/p>\n<h2 class=\"feed4\"><span style=\"color: #ffffff;\">Mode of action of selected yeast postbiotic Safmannan<sup>\u00ae<\/sup><\/span><\/h2>\n<p>[\/vc_column_text][vc_single_image image=&#8221;27&#8243; img_size=&#8221;50&#215;25&#8243; css=&#8221;.vc_custom_1591894886108{padding-top: 5% !important;padding-bottom: 5% !important;}&#8221; qode_css_animation=&#8221;&#8221;][vc_column_text css=&#8221;.vc_custom_1622718598137{padding-right: 10% !important;}&#8221;]<span style=\"color: #ffffff;\">Safmannan<sup>\u00ae<\/sup> ensures excellent, repeatable performance, thanks to its 2 active components, mannans and beta-glucans (1.3 and 1.6).<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ffffff;\">Beta-glucans help modulate the immune system by being in contact with immune cell receptors, triggering them to fight off pathogens.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ffffff;\">Mannans may help to mitigate pathogen colonisation in an animal\u2019s intestinal tract by adsorbing and inhibiting the growth of gram-negative bacteria.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #ffffff;\">Reinforcing the epithelial barrier, and modulating cellular and humoral immunity, contributes to reduce the translocation of bacteria and toxins. Safmannan<sup>\u00ae<\/sup> may help animals to be more resilient, resulting in excellent performance and welfare.<\/span>[\/vc_column_text][\/qode_elements_holder_item][\/qode_elements_holder][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;yes&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; z_index=&#8221;&#8221; anchor=&#8221;presence&#8221; css=&#8221;.vc_custom_1590613349126{padding-top: 2% !important;padding-bottom: 2% !important;}&#8221;][vc_column][vc_column_text css=&#8221;.vc_custom_1591949843691{padding-top: 2% !important;padding-bottom: 2% !important;}&#8221;]<\/p>\n<h2 class=\"feed3\"><span style=\"color: #4c4c4d;\">Your programs with Safmannan<\/span><\/h2>\n<p>[\/vc_column_text][vc_separator type=&#8221;transparent&#8221; up=&#8221;15&#8243; down=&#8221;15&#8243;][vc_row_inner row_type=&#8221;row&#8221; type=&#8221;full_width&#8221; text_align=&#8221;left&#8221; css_animation=&#8221;&#8221;][vc_column_inner width=&#8221;1\/5&#8243;][vc_single_image image=&#8221;396969&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;custom_link&#8221; qode_css_animation=&#8221;&#8221; qode_hover_animation=&#8221;zoom_in&#8221; link=&#8221;\/en\/program-salmo-control\/&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/5&#8243;][vc_single_image image=&#8221;396979&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;custom_link&#8221; qode_css_animation=&#8221;&#8221; qode_hover_animation=&#8221;zoom_in&#8221; link=&#8221;\/en\/program-heat-stress-dairy\/&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/5&#8243;][vc_single_image image=&#8221;396973&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;custom_link&#8221; qode_css_animation=&#8221;&#8221; qode_hover_animation=&#8221;zoom_in&#8221; link=&#8221;\/en\/program-gut-health-piglets\/&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/5&#8243;][vc_single_image image=&#8221;396974&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;custom_link&#8221; qode_css_animation=&#8221;&#8221; qode_hover_animation=&#8221;zoom_in&#8221; link=&#8221;\/en\/program-neonate\/&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/5&#8243;][vc_single_image image=&#8221;396982&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;custom_link&#8221; qode_css_animation=&#8221;&#8221; qode_hover_animation=&#8221;zoom_in&#8221; link=&#8221;\/en\/program-meat-profit\/&#8221;][\/vc_column_inner][\/vc_row_inner][vc_separator type=&#8221;transparent&#8221;][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][vc_column_text css=&#8221;&#8221;]<i>The information provided in this document<span data-olk-copy-source=\"MessageBody\">\/ on this website<\/span> is to the best of our knowledge, true and accurate. Not all products are available in all regions nor are the associated intended uses and\/or claims the same in all regions. Products must only be used in compliance with local laws and regulations and we cannot guarantee freedom for every intended use or country.<\/i>[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; z_index=&#8221;&#8221; anchor=&#8221;sustainability&#8221;][vc_column][qode_elements_holder number_of_columns=&#8221;two_columns&#8221;][qode_elements_holder_item vertical_alignment=&#8221;middle&#8221; horizontal_alignment=&#8221;left&#8221; advanced_animations=&#8221;no&#8221;][vc_single_image image=&#8221;913&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; qode_css_animation=&#8221;&#8221; qode_hover_animation=&#8221;zoom_in&#8221;][\/qode_elements_holder_item][qode_elements_holder_item vertical_alignment=&#8221;middle&#8221; horizontal_alignment=&#8221;left&#8221; advanced_animations=&#8221;no&#8221; item_padding=&#8221;5% 10% 5% 10%&#8221; background_color=&#8221;#ffffff&#8221;][vc_column_text]<\/p>\n<h2 class=\"feed4\"><span style=\"color: #4d4d4c;\">Responding to the needs\u00a0of our customers<\/span><\/h2>\n<p>[\/vc_column_text][vc_single_image image=&#8221;385&#8243; img_size=&#8221;50&#215;25&#8243; css=&#8221;.vc_custom_1591951367255{padding-top: 5% !important;padding-bottom: 5% !important;}&#8221; qode_css_animation=&#8221;&#8221;][vc_column_text]<strong>Packaging<\/strong><\/p>\n<ul>\n<li>25kg polyethylene bag<\/li>\n<li>Big bag 850kg<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong>Shelflife<\/strong><\/p>\n<ul>\n<li>Safmannan<sup>\u00ae<\/sup> offers high stability with its long shelf life of 2 years<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong>Dosage<\/strong><\/p>\n<ul>\n<li>Please reach out to our Phileo experts <span class='highlight' style='color: #333; background-color:#96bb39;'><em><a href=\"\/en\/contact\/\">here<\/a><\/em><\/span><\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_separator type=&#8221;transparent&#8221; up=&#8221;15&#8243; down=&#8221;15&#8243;][\/qode_elements_holder_item][\/qode_elements_holder][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;yes&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; css=&#8221;.vc_custom_1590613392675{padding-bottom: 2% !important;}&#8221; z_index=&#8221;&#8221;][vc_column][vc_column_text css=&#8221;.vc_custom_1590613411511{padding-top: 2% !important;padding-bottom: 2% !important;}&#8221;]<\/p>\n<h2 class=\"feed3\"><span style=\"color: #96bb39;\">Articles<\/span><\/h2>\n<p>[\/vc_column_text][vc_separator type=&#8221;transparent&#8221; up=&#8221;15&#8243; down=&#8221;15&#8243;]<div class=\"qode-news-holder qode-post-carousel1 qode-nl-normal-space\"  data-post-status=publish data-category-name=products data-ignore-sticky-posts=1 data-orderby=rand data-sort=random data-paged=1 data-max-num-pages=0 data-next-page=2 data-title-tag=h4 data-image-size=portfolio-portrait data-display-categories=no data-display-excerpt=no data-display-date=yes data-display-author=no data-display-share=yes data-display-hot-trending-icons=no data-layout=qode_post_carousel1>Sorry, no posts matched your criteria.<\/div>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; el_class=&#8221;breadcrumbtxt&#8221; z_index=&#8221;&#8221;][vc_column][vc_column_text][\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;full_width&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221;][vc_column][qode_elements_holder number_of_columns=&#8221;two_columns&#8221;][qode_elements_holder_item vertical_alignment=&#8221;middle&#8221; horizontal_alignment=&#8221;left&#8221; advanced_animations=&#8221;no&#8221; item_padding=&#8221;5% 10% 5% 0%&#8221;][vc_column_text] Safmannan\u00ae the reference yeast postbiotic for animals\u2019 better performance and resilience [\/vc_column_text][vc_single_image image=&#8221;385&#8243; img_size=&#8221;65&#215;33&#8243; css=&#8221;.vc_custom_1590613257454{padding-top: 5% !important;padding-bottom: 5% !important;}&#8221; 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