{"id":1343,"date":"2020-06-18T12:13:57","date_gmt":"2020-06-18T10:13:57","guid":{"rendered":"https:\/\/demo14.lesaffre.misyl.net\/?page_id=1343"},"modified":"2021-02-02T11:39:58","modified_gmt":"2021-02-02T10:39:58","slug":"layers-gut-health-microbiota","status":"publish","type":"page","link":"https:\/\/phileo-lesaffre.com\/en\/layers\/layers-gut-health-microbiota\/","title":{"rendered":"Layers gut health microbiota modulation"},"content":{"rendered":"

[vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” el_class=”breadcrumbtxt” z_index=””][vc_column][vc_column_text]Phileo by Lesaffre<\/a><\/span><\/span><\/span>[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text]<\/p>\n

[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][qode_elements_holder number_of_columns=”two_columns” custom_class=”tete”][qode_elements_holder_item vertical_alignment=”middle” horizontal_alignment=”left” advanced_animations=”no” item_padding=”5% 8% 5% 0%”][vc_column_text]<\/p>\n

Managing gut health and microbiota modulation<\/span><\/h1>\n

[\/vc_column_text][vc_single_image image=”385″ img_size=”65×33″ qode_css_animation=”” css=”.vc_custom_1590613047306{padding-top: 5% !important;padding-bottom: 5% !important;}”][vc_column_text css=”.vc_custom_1610546108225{padding-right: 8% !important;}”]The objective in layer production is to produce 500 eggs per hen by 100 weeks of age. This creates constant stress for birds due to the passing of protein, fat and energy into their eggs, resulting in chronic physiological inflammation. Some bacteria, like E.coli<\/em>, can profit from this intestinal status, growing and having an impact on gut health. As 70% of the immune system capacity of birds is concentrated in the gut, the smallest enteritis can impact egg production and make birds more sensitive to disease. Maintaining good gut health is important for transforming feed into eggs and protecting farmers\u2019 margins.<\/p>\n

 <\/p>\n

Giving Safmannan<\/a>\u00ae to high performing birds has been shown to reduce the effects of production stress and enhance gut health.[\/vc_column_text][vc_single_image image=”396291″ img_size=”120×178″ alignment=”right” qode_css_animation=””][\/qode_elements_holder_item][qode_elements_holder_item cover=”yes” vertical_alignment=”middle” horizontal_alignment=”left” advanced_animations=”no” background_image=”396300″][\/qode_elements_holder_item][\/qode_elements_holder][\/vc_column][\/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” z_index=””][vc_column][qode_elements_holder number_of_columns=”two_columns”][qode_elements_holder_item vertical_alignment=”middle” horizontal_alignment=”left” advanced_animations=”no” item_padding=”5% 2% 5% 10%” background_color=”#e58734″][vc_column_text]<\/p>\n

Improving gut morphology<\/span><\/h2>\n

[\/vc_column_text][vc_single_image image=”27″ img_size=”50×25″ qode_css_animation=”” css=”.vc_custom_1592227932921{padding-top: 5% !important;padding-bottom: 5% !important;}”][vc_column_text css=”.vc_custom_1610546141339{padding-right: 10% !important;}”]A trial at Shandong Agricultural University, China, in 2015, involved 3 different groups of hens in cages from 12 weeks old to 29 weeks. One group had no supplementation and no density stress (550 cm\u00b2\/layer = low density (Chinese standards). Another group had no supplementation and density stress (333 cm\u00b2\/layer = high density). The third group, supplemented with Safmannan<\/a>\u00ae at 250g\/ton, had high density (HD) stress.<\/span><\/p>\n

Jejunum villi stayed numerically longer in the Safmannan<\/a>\u00ae group, despite the stress, than in the control HD group. Moreover, crypts were significantly less deep in the Safmannan<\/a>\u00ae group compared with the 2 other groups, indicating better gut health. Safmannan<\/a>\u00ae helped preserve better gut morphology under stressful conditions, enabling better feed absorption, and better feed efficiency..<\/span>[\/vc_column_text][\/qode_elements_holder_item][qode_elements_holder_item advanced_animations=”no”][vc_single_image image=”404136″ img_size=”full” alignment=”center” onclick=”link_image” qode_css_animation=”” qode_hover_animation=”zoom_in”][\/qode_elements_holder_item][\/qode_elements_holder][\/vc_column][\/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” css=”.vc_custom_1592234497567{background-color: #ffffff !important;}” z_index=””][vc_column][qode_elements_holder number_of_columns=”two_columns”][qode_elements_holder_item advanced_animations=”no”][vc_single_image image=”404140″ img_size=”full” onclick=”link_image” qode_css_animation=”” qode_hover_animation=”zoom_in”][\/qode_elements_holder_item][qode_elements_holder_item vertical_alignment=”middle” horizontal_alignment=”left” advanced_animations=”no” item_padding=”5% 10% 5% 5%” background_color=”#706f6f”][vc_column_text]<\/p>\n

Preserving tight junction and epithelium integrity<\/span><\/h2>\n

[\/vc_column_text][vc_single_image image=”27″ img_size=”50×25″ qode_css_animation=”” css=”.vc_custom_1592232787710{padding-top: 5% !important;padding-bottom: 5% !important;}”][vc_column_text]A trial was also run by IRTA to assess the effect of Safmannan<\/a>\u00ae on tight junction integrity. The fluorescence method was used, which highlights ZO-1, the main protein comprising the tight junction, at the surface of the villi. The spots of fluorescence were more intense in the Safmannan<\/a>\u00ae group than in the control. This demonstrates improved tight junction integrity, due to Safmannan<\/a>\u00ae, after a local inflammation challenge. This helps reduce the passage of fluids from blood circulation into the gut, thus avoiding leaky gut and wet faeces.<\/span>[\/vc_column_text][\/qode_elements_holder_item][\/qode_elements_holder][\/vc_column][\/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” z_index=””][vc_column][qode_elements_holder number_of_columns=”two_columns”][qode_elements_holder_item vertical_alignment=”middle” horizontal_alignment=”left” advanced_animations=”no” item_padding=”5% 2% 5% 10%” background_color=”#e58734″][vc_column_text]<\/p>\n

Decreasing pathogen pressure and keeping good balance of gut microbiota<\/span><\/h2>\n

[\/vc_column_text][vc_single_image image=”27″ img_size=”50×25″ qode_css_animation=”” css=”.vc_custom_1592232787710{padding-top: 5% !important;padding-bottom: 5% !important;}”][vc_column_text]In the Shandong Agricultural University trial, E.coli<\/em> (potentially pathogenic bacteria), and Lactobacillus (beneficial gut bacteria), were enumerated in ileum and jejunum at 29 weeks, the end of the trial.<\/span><\/p>\n

 <\/p>\n

In each gut area, E.coli<\/em> in the Safmannan<\/a>\u00ae group was significantly reduced, while Lactobacillus was significantly increased, showing better gut microbiota balance, thanks to Safmannan<\/a>\u00ae.<\/span>[\/vc_column_text][\/qode_elements_holder_item][qode_elements_holder_item advanced_animations=”no”][vc_single_image image=”404144″ img_size=”full” onclick=”link_image” qode_css_animation=”” qode_hover_animation=”zoom_in”][\/qode_elements_holder_item][\/qode_elements_holder][\/vc_column][\/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” z_index=””][vc_column][qode_elements_holder number_of_columns=”two_columns”][qode_elements_holder_item advanced_animations=”no”][vc_single_image image=”404148″ img_size=”full” onclick=”link_image” qode_css_animation=”” qode_hover_animation=”zoom_in”][\/qode_elements_holder_item][qode_elements_holder_item vertical_alignment=”middle” horizontal_alignment=”left” advanced_animations=”no” item_padding=”5% 2% 5% 10%” background_color=”#706f6f”][vc_column_text]<\/p>\n

In vitro trials with Safmannan<\/span><\/h2>\n

[\/vc_column_text][vc_single_image image=”27″ img_size=”50×25″ qode_css_animation=”” css=”.vc_custom_1592232787710{padding-top: 5% !important;padding-bottom: 5% !important;}”][vc_column_text]Several in vitro trials have demonstrated the capacity of Safmannan<\/a>\u00ae to bind fimbriae of Gram- bacteria, like E.coli.<\/em> This is useful on commercial layer farms when peaks of mortality, due to E.coli, occur during egg production, when antibiotic treatment is forbidden without egg disposal.<\/span><\/p>\n

 <\/p>\n

The following data comes from an 8000-bird UK breeding farm and 2 layer farms in Poland, each with 60,000 birds. The farmers involved observed a decrease in mortalities within 48 hours following Safmannan<\/a>\u00ae supplementation. E.coli<\/em> gut populations were drastically reduced.<\/span>[\/vc_column_text][\/qode_elements_holder_item][\/qode_elements_holder][vc_separator type=”normal” color=”#ffffff”][\/vc_column][\/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”yes” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” z_index=””][vc_column][vc_separator type=”transparent” up=”10″ down=”10″][vc_column_text css=”.vc_custom_1593403421530{padding-top: 2% !important;padding-bottom: 2% !important;}”]<\/p>\n

Find out more about layers management<\/span><\/h2>\n

[\/vc_column_text][vc_separator type=”transparent” up=”5″ down=”5″][\/vc_column][vc_column width=”1\/4″][vc_single_image image=”396615″ img_size=”full” alignment=”center” onclick=”custom_link” qode_css_animation=”” qode_hover_animation=”zoom_in” css=”.vc_custom_1593403763264{padding-top: 5% !important;padding-bottom: 5% !important;}” link=”\/en\/layers\/layers-salmonella-control\/”][\/vc_column][vc_column width=”1\/4″][vc_single_image image=”396614″ img_size=”full” alignment=”center” onclick=”custom_link” qode_css_animation=”” qode_hover_animation=”zoom_in” css=”.vc_custom_1593403848007{padding-top: 5% !important;padding-bottom: 5% !important;}” link=”\/en\/layers\/layers-gut-health-microbiota\/”][\/vc_column][vc_column width=”1\/4″][vc_single_image image=”396613″ img_size=”full” alignment=”center” onclick=”custom_link” qode_css_animation=”” qode_hover_animation=”zoom_in” css=”.vc_custom_1593403876017{padding-top: 5% !important;padding-bottom: 5% !important;}” link=”\/en\/layers\/laying-performance\/”][\/vc_column][vc_column width=”1\/4″][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” el_class=”breadcrumbtxt” z_index=””][vc_column][vc_column_text][\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text] [\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][qode_elements_holder number_of_columns=”two_columns” custom_class=”tete”][qode_elements_holder_item vertical_alignment=”middle” horizontal_alignment=”left” advanced_animations=”no” item_padding=”5% 8% 5% 0%”][vc_column_text] Managing gut health and microbiota modulation [\/vc_column_text][vc_single_image image=”385″ img_size=”65×33″ qode_css_animation=”” css=”.vc_custom_1590613047306{padding-top:…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":573,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"full_width.php","meta":{"footnotes":""},"class_list":["post-1343","page","type-page","status-publish","hentry"],"yoast_head":"\nManage Layers Gut Health | Phileo by Lesaffre<\/title>\n<meta name=\"description\" content=\"Discover our yeast and bacteria solutions to improve gut morphology, preserve tight junction and epithelium integrity, decrease pathogen pressure and keep good balance of gut microbiota\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/phileo-lesaffre.com\/en\/layers\/layers-gut-health-microbiota\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Layers gut health microbiota modulation\" \/>\n<meta property=\"og:description\" content=\"Managing gut health and microbiota modulation The objective in layer production is to produce 500 eggs per hen by 100 weeks of age. 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