Actisaf® – Premium yeast probiotic

Packaging of thermostable live yeast concentrate - Actisaf HR+
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Thermostable live yeast concentrate - Actisaf


Actisaf® Sc 47 HR+ is a concentrate of live yeast Saccharomyces cerevisiae processed in a microspherule form (Lesaffre proprietary strain: NCYC Sc 47 / CNCM I-4407).
This unique patented Actisaf® Sc 47 micro-spherule form has been developed to deliver unsurpassed intrinsic thermoresistance, without the need for any foreign material coating.

Actisaf® Sc 47 HR+ is designed to be incorporated in pelleted feed thanks to its stability at high temperature up to 92°C.

Key benefits

Dairy cattle

Cow, goat, ewe, buffalo

↓ ruminal acidosis
↑ milk yield
↑ milk solids

Cattle for fattening

Beef, lamb

↓ ruminal acidosis
↑ average daily gain
↑ feed efficiency

Gestating and lactating mare

↑ colostrum and milk immunological and nutritional properties
↑ immune acquisition by the foal at birth

Adult horse

↑ digestive comfort and welfare
↑ body condition
↑ recovery

Gestating and lactating sow

↓ sow body weight loss during lactation
↑ IgG content and nutritional quality of colostrum
↑ IgA content and nutritional quality of milk
↓ risk of neonatal diarrhoea in suckling piglets
↑ litter weight at weaning

Fattening pig

↑ average daily gain
↑ feed efficiency
↓ intestinal disorders
↑ carcass quality

Fattening rabbit

↓ mortality
↑ average daily gain

Mode of action


  • Strengthens the reducing power of rumen:
    • ↑ lactate-utilizing bacteria
    • ↑ cellulolytic bacteria
  • Improves fiber digestion
  • Increases rumen pH by avoiding the build up of lactic acid


  • Improves and stabilises microflora balance
  • Improves fiber digestibility
  • Increases production of Volatile Fatty Acids
  • Limits pathogen multiplication and adhesion on the enterocytes
  • Reduces intestinal inflammation
  • Decreases E. coli shedding


  • Improves microflora balance in the caecum
  • Enhances fiber digestibility
  • Limits overproduction and accumulation of lactic acid in the caecum


  • Improves microflora balance in the caecum
  • Enhances fiber digestibility


  • 25 kg polyethylene bag
  • 1000 kg polypropylene woven big bag with inside polyethylene liner

EU Registration

EU registration number: 4b 1702
Category: Zootechnical additives – Gut flora stabilisers or digestibility enhancers.

The information provided in this document is at the best of our knowledge, true and accurate. However, products must only be used in compliance with local laws and regulations and we cannot guarantee freedom of use for every intended application or country.

Other forms

Live yeast concentrate - Actisaf INST

  • Non-pelleted feed
  • Liquid feed

Live yeast concentrate - Actisaf PWD

  • Mash feed & minerals
  • Thermoresistance up to 60°C

Thermostable live yeast concentrate - Actisaf STD

  • Pelleted feed
  • Thermoresistance up to 83°C

Actisaf® is part of Program Neonate®

Actisaf® is part of Program Heat Stress®

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